Retinol-peel 4% – 30 ml Vedara Medical (M888)
- Intensive rejuvenating, anti-wrinkle, whitening and lifting treatment.
A unique new generation peeling with active retinol, which is converted into retinoic acid in the skin. Thanks to this, the peeling action provides a powerful treatment result for the entire spectrum of the main skin problems: anti-aging and dryness, pigmentation, acne and excessive sebum secretion, photo-damage of the skin with visible results in just 1 month.
Unique features of the peeling action:
Molecular and gene level
- increases collagen synthesis
- suppresses matrix and metalloproteinases (MMP) and reduces collagen degradation
- stimulates the expression of Ki-67
- increases the deposition of glycosaminoglycan in the epidermis
- inhibits tyrosinase activity and melanin content.
Structural and functional level
- improves the organization of collagen and elastin fibers in the papillary dermis
- improves the structure of the dermo-epidermal junction
- thickens the epidermis and thickens the stratum corneum
- inhibits the transfer of melanosomes.
- reduces the appearance of wrinkles and folds
- increases the firmness and elasticity and smoothness of the skin
- reduces roughness of the skin
- reduces photodamage, pigmentation and evens out skin tone.
Method of application: Attention! For the correct application of the peeling, it is necessary to undergo training or follow the exact protocol, taking into account the contraindications. Apply 2 ml of the product to cleansed and prepared skin, bypassing the lips and eye area. After 20-30 minutes, rinse the peeling with water, apply Aloe Pure Natural Gel and massage into the skin. Complete therapy with an Intensive Regeneration day & night Cream or Retinol Cream 0,3%.
After peeling for 2-3 days, you will feel tightening, dry skin, tingling, redness and other unpleasant sensations may occur. On days 2-3, exfoliation of the surface layer of the skin will begin and will last up to 7-10 days but at the same time, if using the products for home care, the patient can can continue to carry on as usual.
Important! It is necessary to use Aloe Pure Natural Gel and any protective cream SPF30-50 from the Vedara Medical line for 3-4 weeks after the in home care therapy, as well as the Intensive Regeneration day & night Cream or Retinol Cream 0,3%.
Active ingredients: retinol, squalene, lactobionic acid, triglycerides, vitamin E, propylene glycol.
A bit of science
After retinol enters the cell by diffusion, it metabolizes to retinoic acid (RA). Abundant retinol is stored as retinyl ester until
needed, or it is cleaved by enzymes as polar metabolites (4-OH-RA). Retinol enhances the expression of specific cellular receptors, such as the cell type 2 retinoic acid binding protein (CRABP-2). 3 Retinoic acid is transported from the cytoplasm to the nucleus by CRABP-2. There, retinoic acid binds to the retinoic acid receptor (RAR), which forms a heterodimer with the retinoid X receptor (RXR).This complex acts as a transcription factor in regions called retinoic acid response elements (RARE) and mediates the expression of genes sensitive to RA, such as type I procollagen (COL1), elastin (ELN), glycosamino- glycan (GAG), tyrosinase (TYR) and Protein Ki-67. These terminal biomarkers can be detected using in vitro methods and are implicated in beneficial anti-aging effects.